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the sleep of dogs caused by a dose of twenty or thirty Zaditor Cost grains of
chloral does Zaditor Price not continue much longer than two hours, unless
the dose be repeated.
Experiment XII. — A dog was put to sleep by twenty
grains of chloral, and her exhalations conducted, as Zaditor Eye Drops in the pre-
vious experiment, through the combustion-tube (porcelain) for
fifteen minutes, and into a silver solution, without producing a
precipitate. The dog was then allowed to take three inspira-
tions of Order Zaditor air impregnated with chloroform, and the exhalations
were conducted as before, in five minutes producing a dense
white precipitate, insoluble in nitric acid, but soluble in am-
monia. The sleep Buy Zaditor Online continued for two hours.
ExPEEiMENT XIII. — Twenty-five grains of chloral were
swallowed by a fasting dog. Generic Zaditor In a very few moments he went
off into Zaditor Tablets a liglit slumber, which lasted five hours. His exhala-
tions from Zaditor Coupon mouth and nostrils were conducted through a red- Buy Zaditor
hot tube into a j)otassa-bulb, containing, as before, the acidu- Alaway Or Zaditor
lated aqueous solution of nitrate of silver. Purchase Zaditor The exhalations
were thus consumed in the tube for one hour and twenty min-
utes, at the end of which time the silver solution was free
from any precipitate, and perfectly clear. The dog was re-
moved from the muzzle, and then half a dozen inspirations of
chloroform were administered, and his exhalations consumed
as before. The silver solution became immediately turbid,
the smell of chlorine was very marked, and a dense white pre-
cipitate was deposited in the silver solution, which was Zaditor Eye Drop insol-
uble in nitric acid, and soluble in ammonia. A portion of
the liquid containing the silver solution was boiled, and oxide
of silver was deposited at the bottom of the test-tube.
ExPEEiMENT XI Y. — A dog was made to swallow forty
grains of chloral, and in fifteen minutes was sound asleep.
His exhalations were conducted through the same apparatus
as before Zaditor Drops described, and thus consumed for three-quarters of
an hour, without interfering in the least with the clearness of
the silver solution. At the end of this time, I introduced
subcutaneously a few drops of chloroform diluted with water,
in the outside of the thigh. In five to ten minutes after, a
white precipitate appeared in the silver solution, which was
i]jsoluble in nitric acid, but soluble in ammonia ; a portion of
WITH CHLOEAL-HYDRATE. 621
the liquid containing the precipitate was boiled, and a me-
tallic oxide of silver was deposited. The place where the
injection was made became inflamed, and an nicer appeared,
which was slow to heal.
These experiments were repeated several times, but in-
variably with the same result, viz. :
That, unless chloroform was administered by inlialation or
by subcutaneous injection, during the sleep caused by chloral,
no chloroform is eliminated by the lungs. It remains to bs Eye Drops Zaditor
seen whether chloroform is present in the urine of a person
taking chloral.
Comparison of Effects of Chloroform, of Chloral-hydrate,
and of Morphia. — I do not desire, in this paper, to enter
into the discussion with regard to the physiological action of
chloroform, as I should not then be able to consider at suf-
ficient length the action of chloral. I have, however, made
several experiments upon the mode of action of chloroform as
an anaesthetic agent, and, as these results have a special bear-
ing upon the important question whether chloral acts by its
slow decomposition in the tissue, I will relate the deductions
that I have drawn from my series of experiments, which have
never yet been published ;
1. The elective action of chloroform for the cerebro-spinal
system, upheld by MM. Lallemand, Perrin, and Duroy, by
Dr. Anstie, and by others, is not yet proved. Tlie experi-
ments undertaken to disprove tliis theory, by Gosselin, by
Snow, and by Richardson, seem to show that, if the brain of Purchase Zaditor Online an
animal is moistened with chloroform, no anaesthesia follows.
2. The injection of chloroform into arteries or veins of any Zaditor Coupons
portion of the body does not cause anaesthesia, unless a sufii-
cient quantity is injected to produce coma or death ; the carotid,
the femoral, and the brachial arteries, were employed in this
method of Buy Cheap Zaditor experimentation. Ko sleep followed, unless coma
and death supervened. It was observed that the chloroform
was absorbed by the tissues, and eliminated by the lungs.
3. Blood was directly transfused from one dog, who was
in a complete state of anaesthesia from the inhalation of
chloroform, to another who had not inhaled Order Zaditor Online chloroform. Five
minutes from the commencement of the transfusion, chloro-
form was exhaled from the lungs of the second dog, though ti
622
EXPEEIMENTS ON ANniALS, ETC.
could not be perceived before. The transfusion was continued
without interruption for from fifteen to twenty minutes, beyond
which time clots were formed in the Cheap Zaditor tube, so as to interfere with
the continuation of the experiment. This experiment was re-
peated several times with the same result. There was not the
slightest appearance of abolition of pain, nor any attempt to
sleep, on the part of the second dog. The transfusions were con-
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